Acne Lesion Counts
Conditions
Keywords
acne, EGCG, green tea
Brief summary
The aim of this study is to investigate the therapeutic effects of green tea extract on acne treatment and related hormone peptides by a double-blinded, randomized and controlled clinical trial.
Detailed description
change in acne lesions counts, hormone, quality of life
Interventions
DIETARY_SUPPLEMENTgreen tea extract EGCG
EGCG, 500mg, tid, 4 weeks
Sponsors
Taipei City Hospital
National Yang Ming Chiao Tung University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Female patient * 20 to 45 years of age * moderate or severe acne vulgaris as defined by the Investigator's Global Assessment (IGA; score of 3 or 4 on a scale from 0 to 5)
Exclusion criteria
* Received systemic retinoid or hormone treatment in the previous 3 months. * Abnormal liver enzymes or kidney function tests (1.5 times higher than the upper normal limit) * abnormal blood chemistry * Pregnant or breast feeding women or the intention of becoming pregnant * Concurrent systemic illness * PCOS * Very severe acne(IGA score5)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acne lesion counts | four weeks |
Secondary
| Measure | Time frame |
|---|---|
| quality of life, SF-12 | four weeks |
Countries
Taiwan
Outcome results
None listed