Hypoventilation
Conditions
Brief summary
The purpose of this study is to determine whether clinical examination, report from ventilator software, nocturnal Sp02 and daytime arterial blood gas are sufficient as screening tools to reveal clinical relevant problems with patients receiving long term treatment with non invasive ventilation.
Detailed description
Patient with chronic hypoventilation with stable on long term treatment (LTMV) with non-invasive ventilation for at least 3 month taking part of our LTMV program will be included. In addition to clinical examination,report from ventilator software, nocturnal Sp02 and daytime arterial blood gas all patients will be investigated with sleep polygraphy and transcutaneous Co2.
Interventions
None listed
Sponsors
Haukeland University Hospital
Trondheim University Hospital
University Hospital, Geneva
Oslo University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Admitted to our unit for optimal treatment of long term non invasive ventilation * Readmitted for control after 6-8 weeks * Then treated for at least 3 month with long term non invasive ventilation outside of hospital. * Informed written consent
Exclusion criteria
* Under 18 years old * Lack of cooperation * Pregnant * Acute exacerbation last 3 month leading to hospital admission. * Change of treatment last 3 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of transcutaneous co2 revealing sleep hypoventilation, when nocturnal pulseoximeter is normal | single night study |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of patient-ventilator asynchrony during non invasive ventilation ? | Single night study |
Other
| Measure | Time frame |
|---|---|
| Comparing rate of event data from ventilator software with manually scored polygraphy during non invasive ventilation | Single night study |
| Technical drift of Transcutaneous Co2 measurement during 8 hours monitoring | One night study |
| Frequency of sleep related breathing events during non invasive ventilation | single night study |
| Accuracy of Transcutaneous monitoring of Co2 compared to arterial carbon dioxide partial pressure | single night study |
| Interscorer variability when scoring polygraphy during Non invasive ventilation | one night study |
Countries
Norway
Outcome results
None listed