Weight Loss
Conditions
Keywords
MMA, AFC, Ovarian reserve
Brief summary
Obesity affects on fertility. Obese women have lower pregnancy rate after infertility treatments.They need more doses of hormone during ovarian stimulation, more days for stimulation. During IVF treatment less oocytes are collected and the quality of embryo also harmed. The first line treatment for those women with obesity and infertility is weight loss. The investigators' hypothesis is that weight reduction improves ovarian reserve and fertility treatment outcome.
Detailed description
The investigators have outpatient clinic for obesity and infertility. the patients undergoing program of 3 months with diet and physical activity. Blood sample will take at the beginning of the program and at the end. The blood sample will evaluate for: AMH, Adiponectin, Leptin, CRP, Colesterol, CRP, Smac in addition TVUS will perform to evaluate AFC.
Interventions
DIETARY_SUPPLEMENTweight loss
Sponsors
Meir Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 43 Years
Healthy volunteers
No
Inclusion criteria
* undergoing weight loss program
Exclusion criteria
* dropp out before comletion the weighy loss target
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anti Mullerain Hormone (AMH)and AFC before and after weight loss | 3 months | AMH and AFC will measure at the first visit and after 3 months of weight loss program |
Countries
Israel
Contacts
Primary ContactAmir Wiswe, MD
Outcome results
None listed