Aged, Asthma
Conditions
Keywords
Acute exacerbation, Quality of life, Magnesium deficiency, Multidisciplinary intervention
Brief summary
We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma. In our previous observational studies, elderly asthma patients had a some distinct features such as impairment of cognitive function, deficiency of micronutrient and absence of caregiver compared with young adult asthmatics. We wanted to evaluate whether the long-term course of asthma could be modified by intervening deficienies which were found in elderly patiensts. So, we designed a interventional study to correct above risk factors in elderly asthma patients, which could be aggravating their asthma. Followings are our specific multidiciplinary items that we want to correct. 1. popularize and educate the asthma action plan 2. run a emergency call system for acute exacerbation 3. educate the proper techniques using inhalers 4. correct the deficiency of magnesium (magnesium 500 mg per day) After 1 years, we will measure the numbers of acute exacerbations, lung function including FEV1 and FEV1/FVC, health-related quality of life and level of serum magnesium in study patients.
Interventions
DIETARY_SUPPLEMENTMagnesium
BEHAVIORALEducation for asthma action plan
BEHAVIORALhot-lines for acute exacerbation of asthma
BEHAVIORALInhaler technique training
Sponsors
Korean Center for Disease Control and Prevention
Sang-Heon Cho
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* elderly asthma patients who had experienced acute exacerbation of asthma 1)aggravations of any of major criteria * dyspnea * cough * wheezing * increase or purulent changes of sputum * nocturnal symptoms 2)aggravation of more than one of following criteria * a reduction of forced expiratory volume at one second or peak expiratory flow rate more than 20% compared than one's best score * unscheduled clinic or emergency department visit or admission * step-up of dose of asthma medications or any intake of systemic steroids
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of acute exacerbation of asthma | 1 year from enrollment | measure the existence of acute exacerbation when they visit the clinic at 3, 6, 12 month after enrollment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pulmonary function test | 1 year after enrollment | measure when subjects visits the clinic at 3, 6, 12 month after enrollment |
| Asthma control status | one year from enrollment | measure when subjects visit the clinic at 3, 6, 12 month after enrollment |
| asthma quality of life questionnaire | one year from enrollment | measure when subjects visit the clinic at 3, 6, 12 month after enrollment |
| serum magnesium level | one year from enrollment | measure when subjects visit the clinic at 3, 6, 12 month after enrollment |
Countries
South Korea
Outcome results
None listed