Association of Carotid Arterial Circumferential Strain With Left Ventricular Function and Hemodynamic Compromise During Off-pump Coronary Artery Bypass Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01840969

Enrollment

Registered

2013-04-26

Start date

2011-09-30

Completion date

2013-02-28

Last updated

2013-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Three Vessel Coronary Artery Disease

Keywords

off-pump coronary artery bypass surgery, common carotid artery, speckle tracking analysis, peak strain

Brief summary

This study is aimed to evaluate the association of common carotid artery circumferential strain with the echocardiographic parameters of left ventricular function and the degree of actual hemodynamic deterioration in patients undergoing multi-vessel off-pump coronary artery bypass with preserved left ventricular ejection fraction.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

1. three vessel coronary artery disease 2. sinus rhythm

Exclusion criteria

1. New York Heart Association functional class ≥3 2. known pulmonary hypertension 3. known valvular heart disease 4. serum creatinine ≥2.0 mg/dL 5. myocardial infarction within 1 week before the surgery 6. history of cerebral or peripheral arterial occlusive disease

Design outcomes

Primary

Measure	Time frame	Description
TTE parameters	1 day before the surgery	TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em

Secondary

Measure	Time frame	Description
change of intraoperative hemodynamic variables	from after induction of anesthesia, left circumflex artery grafting, and to sternum closure	TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em Carotid circumferential strain : Storage of transverse image of the right CCA at approximately 1cm proximal to the bifurcation, manual trace of luminal-intimal border and automatic tracking by frame-to-frame movement of ultrasound reflections (speckles) Hemodynamic variables: cardiac index and mixed venous oxygen saturation obtained from the pulmonary artery catheter and cardiac output monitoring devices

Countries

South Korea

Outcome results