Unspecified Disorder of Vestibular Function, Bilateral
Conditions
Keywords
Circadian Rhythm, Exercise, Reflex, Vestibular Ocular, Postural Balance
Brief summary
The purpose of this study is to study the relationship between the vestibular system and chronobiology
Detailed description
The purpose of this study is to study the relationship between the vestibular system and chronobiology. Two parts will be performed. In the first one patients with bilateral vestibular areflexia will be compared to control subjects. In the second the effect of vestibular stimulation on circadian rhythms will be evaluated
Interventions
BEHAVIORALvestibular stimulation
Physical activity and vestibular stimulation will be used in order to improve circadian rhythms
Sponsors
University Hospital, Caen
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* No treatment changing vigilance/wakefulness * Moderate caffein uptake (2 to 3 cups a day) * Moderate smoker (5 cigarettes a day) * Regular sleeping habits
Exclusion criteria
* Sleeping duration \<6 hours or \>9 hours * Night workers * Pregnancy * Sleep or wakefulness disorders * Progressive neurodegenerative disorders * Progressive psychiatric disorders * Thyroid disease * Type 1 diabetes * Not able to practice physical activity * Drug or alcohol addiction during the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measurements of vestibular reflexes (ocular and spinal) and circadian rhythms of biological functions. | 3 years | Gain of vestibular ocular reflex Amplitude of vestibular spinal reflex Amplitude and phase of temperature circardian rhythms |
Countries
France
Contacts
Primary ContactPierre Denise, MD PhD
Outcome results
None listed