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Prognostic Factors for Acute Pulmonary Embolism in Critically Ill Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01839266
Enrollment
200
Registered
2013-04-24
Start date
2011-11-30
Completion date
2013-04-30
Last updated
2013-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pulmonary Embolism (PE)

Keywords

acute PTE, prognostic factors

Brief summary

Acute pulmonary embolism (PE) is an important cause of in-hospital mortality and may be rapidly fatal if not diagnosed and treated. Despite recent advances in diagnostic and therapeutic modalities, it is still one of the important causes of hospital mortality. Previous several reports have described the variable outcome of patients with PE with reported mortality rate ranging from 8.1% (stable patients) to 25% (with cardiogenic shock) and 65% (post cardiopulmonary resuscitation). Nevertheless, there are no published studies from Korean hospitals that assessed the outcome of acute PE treated in the hospital with IV unfractionated heparin. We conducted this study to determine the outcome, risk factors, clinical characteristics and demographics of patients with acute PE and to identify possible demographic and clinical factors associated with prognosis.

Interventions

None listed

Sponsors

Yonsei University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
34 Years to No maximum
Healthy volunteers
No

Inclusion criteria

patients admitted to the Severance Hospital, Yonsei University Health System with primary diagnosis of PE between January 2008 and December 2012. (diagnosed by CT and treated in the hospital with IV unfractionated heparin)

Exclusion criteria

1. diagnosis was prior to arrivalor 2. anticoagulation was contraindicated 3. diagnosis was not confirmed by CT

Design outcomes

Primary

MeasureTime frameDescription
prognostic factors of overall survivalchange of acute pulmonary embolism(PE) for duration of hospital stay an expected average of 12 monthsIn-hospital all-cause mortality with acute pulmonary embolism(PE) treated in the hospital with IV unfractionated heparin

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026