Sore Throat
Conditions
Keywords
anesthetics,, local,, lidocaine;, nebulizers and vaporizers;, complications,, intubation,, intratracheal.
Brief summary
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
Detailed description
Sudden increases in blood pressure and heart rate after tracheal intubation and post-operative sore throat are two common undesirable side effects of general anesthesia and might lead to patients' morbidity or dissatisfaction. We investigated the possibility to attenuate both side effects with one single method, i.e. ultrasound-driven lidocaine inhalation immediately before induction.
Interventions
DRUGLidocaine inhalation
Lidocaine inhalation before intubation
DRUGPlacebo
Sponsors
New Taipei City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists (ASA) physical status I or II. Patients scheduled for elective surgery under general anesthesia with orotracheal intubation
Exclusion criteria
* patient's refusal to join, major surgery or expected operation duration longer than 3 hours, patients with a anticipated difficult airway, requiring a nasogastric tube in peri-operative stage, having recent upper respiratory tract infection (within 1 week) or pre-existing sore throat.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure | 3 min | Non invasive blood pressure every min for 3 min |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Post operative sore throat | 3 days | Questionnaire for Post operative sore throat |
Countries
Taiwan
Contacts
Primary ContactChen Yen Po, MD
Outcome results
None listed