Prevalence of HbA1C in Women With PCOS

Prevalence of HbA1C in Different Categories of Obesity in Women With PCOS'A Propective Randomized Control Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01838122

Acronym

WHI

Enrollment

300

Registered

2013-04-23

Start date

2013-04-30

Completion date

2013-11-30

Last updated

2013-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin Resistance, Non-insulin Dependent Diabetes Mellitus, Pelvic Endometriosis, Polycystic Ovarian Syndrome, Tubal Obstruction

Keywords

PCOS, HbA1C, Insulin resistance, OGTT, HOMA-IR, HOMA-B-cell

Brief summary

Women with PCOS have been observed to be potential diabetics.Recently,American Diabetes Association has suggested screening of women with PCOS for HbA1C.

Detailed description

In view of recent suggestion of American Diabetes Association(ADA)to screen women with PCOS for HbA1C,we intend to study its prevalence in all categories of obesity in women with PCOS. Women with PCOS by Rotterdam criteria will be screened for insulin resistance by using different techniques or tests. Further, the sensitivity and specificity of HbA1C will be compared with sensitivity and specificity of other insulin resistance markers such as OGTT, Free androgen index, free testosterone, fasting insulin to glucose ratio, HOMA-IR and HOMA-B-CELL.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

15 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

1. BMI of 25-35 Kg/Mt2 2. Atleast three of the Rotterdam criteria for diagnosis of PCOS. 3. Subjects with well stabilized Thyroid,if they had documented evidence of previousthyroid disorder.

Exclusion criteria

1. Subjects with documented diagnosis of Metabolic Syndrome. 2. Subjects with laparocopic and histopathologic diagnosis of Endometriosis. 3Subjects with Primary hyperprolectineamia. 4.Subjects with basal FSH \>/=15mIU/ml. 5.Subjects with continuously elevated 17-0h-p.

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of HbA1C in both arms of the cohort of subjects	September 2013	HbA1C has been suggested as a potential marker for NIDDM in subjects with PCOS

Countries

India

Outcome results