Lung Cancer, Non Small Cell Lung Cancer
Conditions
Keywords
Surgery, NSCLC
Brief summary
Empyema following pneumonectomy for Non Small Cell Lung Cancer (NSCLC) is a known problem that occurs in about 2% of pneumonectomy patients.
Detailed description
The development of an empyema following pneumonectomy is a devastating complication, especially if associated with an underlying fistula. Whilst the perioperative mortality of pneumonectomy overall is now less than 5%, this rises to around 25% when complicated by empyema, and about 50% when associated with fistula. In addition, there is the morbidity and social cost of long-term drainage, chronic sepsis and often multiple operations.
Interventions
None listed
Sponsors
University Hospital, Gasthuisberg
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pneumonectomy for NSCLC
Exclusion criteria
* Pneumonectomy for other reasons (infectious pathology, trauma, mesothelioma, ...)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | 5 years from surgery | overall 5-year survival after empyema following pneumonectomy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| incidence rate | 1 and 5 years from surgery | incidence of empyema, accompanied with broncho-pleural fistula or not, divided in short term (less than 1 yr postoperatively) and long term (up to 5 years postoperatively) incidence. |
Other
| Measure | Time frame | Description |
|---|---|---|
| fast track treatment outcome | 5 years from surgery | over the last 7 years, a new approach - known as 'fast track treatment of Empyema following pneumonectomy (EFP)' is used. We will examine if there is a benificial aspect in this approach, regarding survival en hospital stay. |
Countries
Belgium
Outcome results
None listed