Delirium, Renal Failure, Septic Shock
Conditions
Brief summary
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium. The aim of this pilot study is two fold. First, to determine the feasibility and potential challenges of measuring cerebral oxygenation in ICU patients with severe sepsis and septic shock. And second, to see if the incidence and magnitude of cerebral desaturations correlated with ICU acquired delirium as measured by the Confusion Assessment Method (CAM) scores.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Over 18 * Diagnosis of septic shock * Require mechanical ventilation and vasopressor therapy
Exclusion criteria
* Previous stroke * Dementia * Recent Craniotomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Delirium | 28 Days |
Secondary
| Measure | Time frame |
|---|---|
| Death | 28 Days |
Other
| Measure | Time frame | Description |
|---|---|---|
| Renal Failure | 28 Days | Defined using RIFLE Criteria |
Countries
Canada