Uterine Masses
Conditions
Brief summary
Colour Doppler sonography has also been evaluated in differentiating adenomyosis from fibroids. Two dimensional color Doppler ultrasound revealed that 87% of adenomyosis cases had vessel distributions different from those found in leiomyoma cases, in addition to a high pulsatility index (PI) .Adenomyotic lesions had randomly scattered vessels or intratumoral signals while leiomyomas usually had peripheral scattered or outer feeding vessels.
Detailed description
Because it is more sensitive, less angle-dependent, and not susceptible to aliasing , power Doppler Sonography has the potential to detect fluctuations in blood flow , with results superior to those of frequency-based color Doppler sonography, particularly in situations of low-velocity blood flow. Three dimensional power Doppler ultrasonography can be applied to differentiate between uterine adenomyosis and leiomyoma ,and it may reduce the number of false positives by detailed investigations.
Interventions
OTHERThree dimensional Power Doppler to the myometrial mass
Trans-vaginal 3D power Doppler Ultrasonographic examination will be done for all participants prior to surgery. The ultrasonographic examination will provide data related to lesion size, lesion volume, vascular location (location), vascular index (VI), flow index (FI), and vascular-flow index (VFI). The region of interest will include the entire region of the uterine mass. The virtual organ computer aided analysis (VOCAL) software for the analysis of 3D power Doppler histograms will be used with computer algorithms to form indices of blood flow and vascularization. All data will be collected and compared with the post operative histopathology results.
uterine artery Doppler indices(RI,PI) are measured for all cases with myometrial mass
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Age between 20 & 60 years. * Asymptomatic pts which discover the mass accidentally . * Patients with symptoms like menorrhagia, menometrorrhagia, dysmenorrheal , abdominal masses. * Patients scheduled for hysterectomy(abdominal/vaginal or Laparoscopic) * Patients scheduled for myomectomy.
Exclusion criteria
* Pregnant patients * Age over 60 or under 20years. * Conservative management (Non surgical)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Power Doppler Vascular indices | 9 months | The ultrasonographic examination will provide data related to lesion size, lesion volume, uterine artery doppler indices and vascular location (location), vascular index (VI), flow index (FI), and vascular-flow index (VFI). The region of interest will include the entire region of the uterine mass. The virtual organ computer aided analysis (VOCAL) software for the analysis of 3D power Doppler histograms will be used with computer algorithms to form indices of blood flow and vascularization. All data will be collected and compared with the post operative histopathology results. |
| Uterine artery doppler indices in fibroids in relation to adenomyosis | 9 months | Uterine artery doppler indices(RI,PI) in fibroids in relation to adenomyosis |
Countries
Egypt
Contacts
Primary ContactEman A. Elkattan, M.D,MRCOG
Outcome results
None listed