Erectile Dysfunction
Conditions
Brief summary
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come. Currently, the mechanism of ED is not fully understood. MicroRNAs (MiRNA) are endogenous small RNA molecules that control gene expression post-transcriptionally. It has been included in many in vitro physiology and pathophysiology processes, which also involved in the process of ED. This research was designed to investigate the differential plasma MiRNA profiles in ED and normal erectile function in older males. The results might tell us which MiRNA and how did it involved in the process of ED in aging.
Interventions
OTHERTake blood
Sponsors
Nanjing Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* older males with erectile dysfunction
Exclusion criteria
* have some other general diseases, e.g. hypertension, vascular diseases, depression, chronic kidney disease, diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene chips | 30 days |
Secondary
| Measure | Time frame |
|---|---|
| RT-PCR | 15 days |
Countries
China
Contacts
Primary ContactFeng Pan, Doctor
Outcome results
None listed