Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Endometrial Ablation

Autocrosslinked Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Bipolar Radiofrequency Endometrial Ablation: a Randomised, Controlled and Double Blind Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01829451

Enrollment

Registered

2013-04-11

Start date

2011-01-31

Completion date

2012-08-31

Last updated

2013-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menorrhagia

Brief summary

The aim of the study is to evaluate if hyaluronic acid gel prevents intrauterine adhesion formation after endometrial thermal ablation.

Interventions

OTHERHyaluronic acid gel

Hyaluronic acid gel is placed into the uterus after endometrial ablation \--------------------------------------------------------------------------------

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

35 Years to 52 Years

Healthy volunteers

Yes

Inclusion criteria

* menorrhagia

Exclusion criteria

* abnormal uterine cavity, * abnormal endometrial biopsy

Design outcomes

Primary

Measure	Time frame	Description
prevention of intrauterine adhesion formation	3 months	The effect of hyaluronic acid gel on the formation of intrauterine adhesions after endometrial thermal ablation is assessed in an outpatient hysteroscopy after 3 months. Classification of intrauterine adhesions has been created for this study specifically.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026