Skip to content

Effect of American Ginseng on Exercise-induced Muscle Soreness

Effect of American Ginseng on Exercise-induced Muscle Soreness

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01827696
Enrollment
10
Registered
2013-04-09
Start date
2013-05-31
Completion date
2013-12-31
Last updated
2016-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Damage

Keywords

Muscle, Soreness, Muscle function, Damage, Ginseng

Brief summary

Healthy participants will ingest American ginseng daily or a placebo for four weeks prior to engaging in a unaccustomed exercise bout designed to induce mild-moderate muscle soreness. Muscle soreness will be assessed via decrements in muscle strength and with a self-rating of perceived soreness before and several times after the exercise.

Detailed description

Healthy men and women will consume either 2000 mg of American ginseng daily (four 500 mg pills will be taken at four different times during the day always with food/meals) or a placebo (4 cellulose) for four weeks prior to engaging in a 40 minute downhill treadmill jog (12% decline) at a speed of 7 miles per hour. Participants will consume one pill with breakfast, one pill with lunch, one pill with dinner and another pill with a snack either between meals or prior to bedtime. The exercise will be consist of five, eight minute bouts of jogging with two minutes of rest/recovery in between. The degree of muscle soreness will be assessed using a Biodex strength testing machine (isometric and concentric isokinetic torque), and a self-rating of perceived soreness on a scale from zero to ten. All of the above measures will be taken before and several times after the downhill jogging protocol.

Interventions

DIETARY_SUPPLEMENTGinseng

Effect of four weeks of daily Ginseng intake (2gm/day) on muscle soreness following downhill running exercise

Sponsors

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy men or women, (women must weigh between 55-65 kg., while men must weigh between 75-85kg). * Participants must not have engaged in any endurance run training in the past 9 months.

Exclusion criteria

* Injured * Regular runners * Pregnant (or with any chance they may become pregnant) * Breast-feeding * Diabetics or those taking medication for diabetes * Insomniacs * Schizophrenics * Hyper- or hypotension * Cancer * Irregular heartbeats * Heart disease * Females with endometriosis or uterine fibroids * Those who have surgery scheduled during the study or within the two weeks following the completion of the study * Those taking warfarin or medication for depression.

Design outcomes

Primary

MeasureTime frameDescription
muscle strength1 monthginseng & muscle strength

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026