Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation

Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01826955

Acronym

rSO2pneumo

Enrollment

Registered

2013-04-09

Start date

2013-04-30

Completion date

2014-07-31

Last updated

2015-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumoperitoneum

Keywords

pneumoperitoneum, cognitive function

Brief summary

The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.

Detailed description

Laparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in haemodynamic variables, regional cerebral oxygen saturation, and early postoperative cognitive function in patients undergoing laparoscopic gastrectomy in the reverse Trendelenburg position with those patients that underwent conventional open gastrectomy.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* ASA class I or II, aged 20 to 70 yrs

Exclusion criteria

* Patients with morbid obesity (body mass index \> 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.

Design outcomes

Primary

Measure	Time frame	Description
MMSE	5days after end of surgery	5 days after operation MMSE (mini-mental status exam)was recorded

Countries

South Korea

Outcome results