Monopolar Depression, Single Episode or Unspecified, Suicidal and Self-injurious Behaviour
Conditions
Brief summary
The purpose of this study is to combine and adapt Mindfulness-Based Cognitive Therapy (MBCT) + Safety Planning Intervention (SPI) for individuals with suicidal behavior and to determine its feasibility, acceptability, safety and preliminary effectiveness. An exploratory aim is to collect data on the cognitive changes underlying treatment gains.
Detailed description
* The study is a nine-week clinical trial combining Safety Planning Intervention plus Mindfulness-Based Cognitive Therapy for patients with a recent history of suicidal thoughts or behavior and current or past depressive symptoms. * These treatments work for depression and some preliminary data suggest they may work to prevent suicidal behavior. * Participation includes: * Nine weeks of free treatment * Clinical assessments * An opportunity to offer your views on treatment and suggestions for improving the treatment in focus groups
Interventions
BEHAVIORALMBCT+SPI
Safety Planning Intervention (SPI), a very brief intervention focused on identifying personalized coping strategies to manage acute suicidality, is combined with Mindfulness-Based Cognitive Therapy (MBCT), a group intervention comprised of mindfulness training and cognitive therapy techniques. Treatment lasts 9 weeks.
Sponsors
American Foundation for Suicide Prevention
New York State Psychiatric Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* 18-65 * History of depression * Suicidal behavior or thoughts (i.e., current suicidal thoughts at screening and history of at least one suicide attempt or suicide-related behavior (aborted or interrupted suicide attempt) or suicidal ideation with plan or method in the past 6 months) * In active treatment (e.g., receiving psychiatric medications)
Exclusion criteria
* Current mania, psychosis, Obsessive-Compulsive Disorder, Traumatic Brain Damage, Organic or Acute Brain Syndrome, Mental Retardation or pervasive developmental disorder * Requires priority treatment for an acute illness or debilitating problem such as severe primary substance dependence or anorexia nervosa * Inability to complete psychiatric interview or group treatment due to lack of cooperation or lack of comprehension.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Retention | participants will be followed for the duration of treatment, an expected average of 9 weeks | Feasibility |
| Consumer Satisfaction Questionnaire | post-treatment (at 9 weeks) | Acceptability |
| Change in scores on Scale for Suicide Ideation | participants will be followed for the duration of treatment, an expected average of 9 weeks | Safety |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in scores on Beck Depression Inventory (BDI-II) | baseline and post-treatment (at 9 weeks) | Effectiveness |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in cognitive processes underlying treatment gains | baseline and post-treatment (at 9 weeks) | neuropsychological tasks assessing attention and other cognitive processes |
Countries
United States
Outcome results
None listed