Virtual LV Lead Navigation in Patients With Ischemic Cardiomyopathy

Virtual Left Ventricular Lead Navigation in Patients With Ischemic Cardiomyopathy

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01825239

Enrollment

Registered

2013-04-05

Start date

2014-04-30

Completion date

2014-10-31

Last updated

2015-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiomyopathy, Ischemic Cardiomyopathy

Keywords

ischemic cardiomyopathy, cardiomyopathy, left ventricular lead, cardiac electrophysiologic studies

Brief summary

Presently, the left ventricular lead is placed in a similar position for all patients. It is not known whether placing this lead in different positions in the heart will make the heart pump better. In this study, the investigator will collect measurements of the heart's electrical activity during an Electrophysiology Study (EP study or EPS). The hope is that these measurements will provide the know how to develop an individualized left ventricular lead placement prescription for patients referred for left ventricular lead pacing.

Interventions

OTHERCollection of measurements during LV pacing during electrophysiology study

During the electrophysiology study, measurements will be obtained while pacing from different left ventricular regions in context to scar as determined by SPECT-CT testing.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Ischemic cardiomyopathy * Intrinsic QRS duration \>120 milliseconds * LV ejection fraction \<40%

Exclusion criteria

* Persistent atrial tachyarrhythmia * Active cardiac ischemia * Cerebrovascular accident within 6 months * Surgical or percutaneous cardiac revascularization procedure within 3 months * Under 18 years of age * Pregnant * Participating in a clinical study that would preclude enrollment * Unable to provide informed consent

Design outcomes

Primary

Measure	Time frame	Description
dP/dt measurements observed during pacing from different left ventricular regions	Measurements will be observed at the time of the electrophysiology study (EPS) at enrollment.	During the electrophysiology study, the dP/dt measurements will be observed during pacing from different left ventricular regions.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026