Acute Kidney Injury, Critically Ill, Septic Shock
Conditions
Keywords
hemofilter, coagulation, CRRT, critically ill
Brief summary
Compared with AN69 hemofilter, AN69 ST hemofilter may prolong the time of hemofilter and decrease the quantity of heparin during continuous renal replacement therapy in critically ill.
Interventions
DEVICEAN 69 ST hemofilter
DEVICEAN 69 hemofilter
Sponsors
Zhongda Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* age\> 18 years old * admitted to ICU and need CRRT * anticipated survival time \>72h
Exclusion criteria
* allergy to hemofilter or heparin * heparin associated thrombocytopenia * pregnancy or lactation * using other anticoagulate drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The using time of hemofilters | 72h | The time from the beginning of continuous renal replacement therapy until to the end when continuous renal replacement therapy had to be finished because of clotting or other reasons |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| activated partial thromboplastin time | every 6h from the begining of continuous renal replacement therapy,up to 72h | Heparin will be used according to activated partial thromboplastin time, and the quantity will be recorded. |
Other
| Measure | Time frame |
|---|---|
| Number of participants with adverse events during continuous renal replacement therapy | 72h |
Countries
China
Contacts
Primary ContactQiu Xiaohua
Outcome results
None listed