Effects of Maternal Body Composition on Offspring Brain Structure and Function

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01822067

Enrollment

100

Registered

2013-04-02

Start date

2012-08-31

Completion date

2026-12-31

Last updated

2025-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Function

Brief summary

The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

11 Days to 17 Days

Healthy volunteers

Yes

Inclusion criteria

* the participant must be enrolled in the Arkansas Children's Nutrition Center (ACNC) Glowing study and be about 2 weeks of age +/- 3days

Exclusion criteria

* none specified

Design outcomes

Primary

Measure	Time frame	Description
Brain Structure	Age 2 weeks	We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants

Secondary

Measure	Time frame	Description
Brain Function	Age 2 weeks	We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants

Countries

United States

Outcome results