Childhood Body Composition and Brain Structure and Function

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01822054

Enrollment

Registered

2013-04-02

Start date

2012-01-31

Completion date

2014-08-31

Last updated

2023-12-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The specific aim of this research project is to use MRI methods to evaluate and compare brain structure and function in normal weight and obese children age 8-10 years.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

8 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy normal weight or obese children * Parental report of full-term gestation * Parental report of birth weight between 5th-95th percentiles * Parental report of breastfeeding or cow's milk formula fed during infancy * Right hand dominance

Exclusion criteria

* Maternal diabetes * Maternal alcohol, tobacco or drug use during pregnancy * Chronic sleep disorder * History of psychological or psychiatric diagnosis * History of neurological impairment or injury * Surgical implant or other foreign object in the body which may be a MRI safety concern * Dental work which may cause artifacts in MRI * Claustrophobia * High likelihood of inability to tolerate loud noise from the MRI scanner

Design outcomes

Primary

Measure	Time frame	Description
Brain structure	8 - 10 years of age	We will use high resolution volumetric MRI and DTIto measure the brain structure of these children

Secondary

Measure	Time frame	Description
Brain Function	8-10 years of age	We will use high resolution fMRI to measure the brain function under different cognitive paradigms

Countries

United States

Outcome results