Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected IHD

Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected Ischemic Heart Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01821924

Enrollment

2347

Registered

2013-04-01

Start date

2012-01-30

Completion date

2018-08-30

Last updated

2025-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Brief summary

The investigators plan to use retrospective data to assess heart function and structure abnormalities through the use of an approved vasodilating agent for stress cardiac MRI tests. The investigators are interested in how these MRI findings relate to long-term prognosis in people who are at risk for cardiac disease.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Age \>/= 21 years old * No contraindications for cardiac MRI (by renal function or metallic hazards)

Design outcomes

Primary

Measure	Time frame	Description
A composite outcome measure consisting of cardiovascular mortality and nonfatal MI after index CMR.	target follow up of at least 4 years	Myocardial infarction will be defined as hospital admission for acute coronary syndrome (defined by positive serum troponin level with documented electrocardiographic changes, clinical syndrome, or need for percutaneous or surgical revascularization).

Secondary

Measure	Time frame	Description
A composite outcome measure consisting of cardiovascular mortality, nonfatal MI, hospitalization for unstable angina or congestive heart failure, and late unplanned coronary bypass surgery at at least 6 months after index CMR.	target follow up of at least 4 years	Heart failure hospitalization will be defined as any hospitalization for signs and symptoms of volume overload or dyspnea requiring diuretic therapy regardless of LV ejection fraction.

Countries

United States

Outcome results