Focus: Anabolic Response to Food Intake in Young Individuals, Condition Relevance: Skeletal Muscle Health, Sarcopenia
Conditions
Keywords
Muscle protein synthesis, Dietary protein
Brief summary
In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.
Interventions
DIETARY_SUPPLEMENTHigh protein intake
OTHERPlacebo comparator
No protein intake
Sponsors
Maastricht University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Males * Aged between 18-35 years * Healthy, recreationally active * BMI \< 30 kg/m2
Exclusion criteria
* Smoking * Allergies to milk proteins (whey or casein) * Vegetarians * Diagnosed GI tract diseases * Female * Arthritic conditions * A history of neuromuscular problems * Previous participation in amino acid tracer studies * Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle protein fractional synthetic rate following protein ingestion | 3 hours | The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion. |
Outcome results
None listed