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The Influence of Preoperative Cardiopulmonary Capacity on the Perioperative Lactate Level

The Influence of Preoperative Cardiopulmonary Capacity Mesured in MET's (Metabolic Equivalents) on the Perioperative Lactate Level

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01819337
Enrollment
1502
Registered
2013-03-27
Start date
2013-03-31
Completion date
2013-08-31
Last updated
2013-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication, Cardio-respiratory, Sensitivity Training Groups

Brief summary

The aim of this study is to identify if there exists a correlation between the preoperative cardiopulmonary capacity - measured in MET's - and the perioperative lactate serum level.

Detailed description

The determination of the cardiopulmonary (c/p) capacity is very important for the evaluation of every patient undergoing surgery. The ability to climb at least two flight of stairs is seen to be an acceptable c/p capacity for surgery. There are several ways to evaluate the fitness of patients. A common method to estimate the cardiopulmonary capacity is defining patients through the MET's (metabolic equivalents) scale. MET's can be defined relatively easy through a simple questionnaire. Patients with a reduced c/p capacity have less than 4 MET's, patients with a relatively good c/p capacity have 4-10 MET's and patients with a excellent c/p capacity have more than 10 MET's. The lactate level in blood serum is a common parameter to asses anaerobic metabolism in patients. A high lactate level correlates with higher mortality rates and outcome. To yet it is not clear if there exists a correlation between the preoperative cardiopulmonary capacity measured in MET's and the perioperative lactate level. We hypothysed that patients with a reduced cardiopulmonary capacity are associated with higher perioperative lactate levels, as these group of patients compensate the stressors operation/anesthesia less than patients with a good c/p capacity.

Interventions

None listed

Sponsors

University of Witten/Herdecke
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age \> 18 years

Exclusion criteria

* Cardiac surgery

Design outcomes

Primary

MeasureTime frameDescription
lactate - venous blood gas analysisvenous lactate will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hoursmmol/l

Secondary

MeasureTime frameDescription
icu in hospital mortalityicu patients will be followed over their hospital stay over a maximum period of 6 months
hemoglobin - venous blood gas analysishemoglobin will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hoursg/dl
icu ventilation timeicu patients will be followed over their hospital stay over a maximum period of 6 monthshours/days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026