Neuromuscular Disorder, Respiratory Failure
Conditions
Keywords
Neuromuscular disorder, Mechanical ventilation, Speech, Respiratory failure
Brief summary
Mechanical ventilation is one of the only treatment that has improved survival of patients with neuromuscular respiratory failure. As disease progresses, some patients may require longer ventilation period. Non invasive mechanical ventilation is the preferred method of ventilation but it may interfere with speech and communication of patients who require ventilation throughout the day. The investigators are evaluating the effect on speech and communication of a ventilation device which allows patients to momentarily and voluntarily withhold ventilation if they want to speak. This should allow the patients to have a more fluid speech.
Interventions
DEVICEElysee 150 ventilator
DEVICEElysee 150 ventilator with a ventilation switch control
Sponsors
Centre d'Investigation Clinique et Technologique 805
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient with restrictive respiratory failure secondary to a neuromuscular disorder, without any bulbar involvement. * Age greater than or equal to 18. * Hospitalization in Home Ventilation Unit of the intensive care department of R. Poincaré Hospital. * Non invasive mechanical ventilation for a duration equal or above 14h per day. * Patient in a steady state at the time of the study * written informed consent
Exclusion criteria
* patient's refusal to participate to the study * Inability to read the selected text * Inability to use the ventilator switch * Inability to cooperate * Hemodynamic instability * Acute respiratory failure * No affiliation to social security
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Impact of patient's ventilation control on speech efficiency | 1 hour 30 min | Speech efficiency will be evaluated while using a ventilator which allows the patient to constantly control when he wants to be ventilated Speech evaluation is based on speech rhythm and text reading duration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient ventilator synchronisation during speech | 1hour 30 min | Evaluated with the variation of respiratory frequency during speech, the number of auto-triggered ventilation cycles during speech. |
| User friendliness of the ventilator during speech | 1hour 30 min | evaluation of user friendliness by the patient using a visual analogical score |
| Respiratory comfort during speech | 1hour 30 min | evaluation of user friendliness by the patient using a visual analogical score and the Borg score |
| Speech comfort during ventilation | 1hour 30 min | evaluation of speech comfort during ventilation by the patient using a visual analogical score |
Countries
France
Outcome results
None listed