Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01819038

Acronym

EarlyRRT

Enrollment

Registered

2013-03-27

Start date

2013-01-31

Completion date

2015-12-31

Last updated

2016-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Failure

Brief summary

This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in decision- making.

Interventions

PROCEDUREcontinuous renal replacement therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* The patient must have given his/her informed and signed consent * patients with acute kidney injury in the intensive care ward.

Exclusion criteria

* The patient refuses to sign the consent * The patient is pregnant, parturient, or breastfeeding * End stage renal disease * Chronic renal failure * previous kidney transplant

Design outcomes

Primary

Measure	Time frame
mortality rate	28 day

Secondary

Measure	Time frame
ventilator free-days	28 days

Other

Measure	Time frame
hemodialysis free-days	28 days

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026