Miscellaneous Disorders in the Fetus or Newborn
Conditions
Keywords
Carbon monoxide, safety, Adverse Reaction, newborn
Brief summary
Based on the study about carbon monoxide in human inflammatory and other beneficial physiological function , now we'll be going to research its application in neonates .Phase 1 Study as a foundation for the further test is, the safety and Adverse reaction study of newborn to inhaled CO
Detailed description
Previous studies have demonstrated that, carbon monoxide has showed the effectiveness such as in inflammation ,apoptosis as well as relaxation of smooth muscle of the body. Now we have a hypothesis to use carbon monoxide in pulmonary hypertension of the newborns, to observe whether it will decrease pulmonary artery hypertension on newborns. Phase 1 study is ,the safety and Adverse reaction study of newborn to inhaled CO , after this,we can master the application of carbon monoxide dose
Interventions
Inhaled Carbon Monoxide in newborn
Sponsors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
CAN WANG
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Minutes to 1 Months
Healthy volunteers
Yes
Inclusion criteria
* The newborn whose physiological function is healthy or close to healthy
Exclusion criteria
* Clinical considerations cannot survive or no treatment value of newborn Diagnosis of congenital or hereditary diseases, or children with heart diseaseCentral pulmonary vascular malformations in children
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of participants with adverse events | up to 1 month |
Countries
China
Outcome results
None listed