Neuromodulation to Facilitate the Effect of Ketamine

Treatment of Thalamocortical Dysrhythmia Using External Neuromodulation to Facilitate the Therapeutic Effect of Ketamine.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01816958

Acronym

TMS/ketamine

Enrollment

Registered

2013-03-22

Start date

2011-01-31

Completion date

2012-11-30

Last updated

2013-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain, Depression, Substance Abuse

Keywords

thalamocortical dysrhythmia, transcranial magnetic stimulation (TMS), transcranial Electrical Stimulation (tES), (N-methyl-D-aspartate) NMDA-R antagonist, ketamine infusion, neuromodulation, synergistic effect, remission

Brief summary

application of external neuromodulation along with ketamine infusion.

Detailed description

apply TMS concurrent with ketamine infusion in order to increase the likliehood & strength of therapeutic benefit

Interventions

OTHERco-administration of TMS and infused ketamine

co-administration of TMS and infused ketamine

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* chronically ill, * treatment-resistant

Exclusion criteria

* active psychosis

Design outcomes

Primary

Measure	Time frame	Description
Global Assessment of Function in DSM-4R	up to 3 years	treat in order to cause remission of disability

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026