Dysplasia, Hyperplasia
Conditions
Keywords
abnormal histological colorectal lesions
Brief summary
The main purpose is to describe clinical practices nowadays prospectively about patients with a dysplasia diagnosis or another histological lesions. It will be identified colic situation during the initial colonoscopy after dysplasia diagnosis or atypical lesion. Also the frequency and the type of monitoring conducted about these patients(surgical and endoscopic treatments). The main criterion evaluation will be the surgical and endoscopic rates during the time. The treatments offered such as surgical, endoscopic ones or none of them will be followed. Finally, the outcome of these patients: stability, lesion disappearance, surgery or development of cancer with frequencies for each of them and relationships with histological abnormal colorectal lesion will be measured.
Detailed description
A replay centralized pathological lesion slides corresponding to the different lesion will be done
Interventions
None listed
Sponsors
Hôpital Edouard Herriot
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* intestinal chronic inflammatory disease with at least one lesion such as hyperplasia or no dysplastic scalloped lesion, dysplastic scalloped lesion or low grade dysplasia or high grade dysplasia * compliant patient * endoscopic follow possible * no settler cancer * no serious pathology such as cancer
Exclusion criteria
* settler cancer * serious pathology such as cancer * no compliant patient * endoscopic follow not possible
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| endoscopies results | 4 years | rates of surgery and endoscopic treatments frequency of development of a cancer or a high grade dysplasia according to a type of abnormal histological colorectal lesion |
Countries
France
Outcome results
None listed