Caffein Consumption and Response Inhibition

Does Caffeine Consumption Improve Response Inhibition to Food Cues?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01815203

Enrollment

Registered

2013-03-20

Start date

2013-03-31

Completion date

2013-08-31

Last updated

2013-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Behavior, Obesity

Keywords

Caffeine effects, Inhibitory control

Brief summary

With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy levels. One of the factors that is potentially important in response inhibition is caffeine. The aim is to assess the direct effects of caffeine on response inhibition, using a No Go/Go-task. We will also assess whether the presentation of food cues, i.e. as words or as pictures, modulate response inhibition different in restrained vs. non-restrained eaters.

Detailed description

In a blinded, randomized cross-over design, participants will receive either a capsule with caffeine or placebo at two separate occasions whereupon study tasks will be performed.

Interventions

DRUGCaffeine

Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test.

DRUGPlacebo

Administration of placebo with subsequent cognitive tasks and food test.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Only males * 18 ≤ 35 years * Healthy (self rated) * Used to drink caffeine * Used to eat breakfast regularly (≥ 5 times a week). * Non-smokers

Exclusion criteria

* BMI outside the range of 18,5 ≤ 25 * hypersensitivity for the ingredients of the foods under study * being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea * Presence of any chronically disease and/or treatment with medication

Design outcomes

Primary

Measure	Time frame	Description
Inhibition control	20 min	Measurement inhibition control via a computer test (NoGo-Go task.

Secondary

Measure	Time frame	Description
Food test	20 min	Measure of participants food intake.

Other

Measure	Time frame	Description
Blood sample	5 min (1 sample)	Blood glucose assessment in order to confirm fasted condition prior to study experiments.

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026