Twentyfour Ambulatory Pulse Wave Velocity and Central Augmentation Index in Type 2 Diabetes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01812811

Enrollment

Registered

2013-03-18

Start date

2012-09-30

Completion date

2013-07-31

Last updated

2013-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

pulse wave analysis, pulse wave velocity, Arteriograph24, Ambulatory, diabetes, reproducibility, diurnal variation

Brief summary

The functionality and reproducibility of pulse wave analysis is investigated in 20 type 2 diabetic patients who had two 24 hour measurements performed within one week with the Arteriograph24 equipment.

Detailed description

Arteriograph24 is a new monitor for measuring ambulatory blood pressure and additional performing brachial cuff based on analysis of a suprasystolic pulse wave. The study aim to test the feasibility of ambulatory pulse wave analysis every twenty minute (the fraction of missed measurements)and the reprodicility of pulse wave velocity and central augmentation index in type 2 diabetic patients. In addition we will explore the relation between diurnal variation of brachial blood pressure, central blood pressure and pulse wave velocity. 20 type 2 diabetic patients will have 24h ambulatory blood pressure performed twice with an interval of one week.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Type 2 diabetes

Exclusion criteria

* Atrial fibrillation

Design outcomes

Primary

Measure	Time frame	Description
Fraction of missed pulse wave analysis	Meaured two times with an interval of one week	Measurements of ambulatory blood pressure and pulse wave analysis is performed every twenty minute. The fraction of missed measurements of pulse wave analysis during day time and night time analysis is the final outcome

Secondary

Measure	Time frame	Description
Reproducibility of pulse wave analysis parameters	Measured two times with an interval of one week	Reproducibility of pulse wave velocity, Central systolic blood pressure and central augmentation index for 24 hour, day and night

Other

Measure	Time frame	Description
Diurnal variation of brachial blood pressure, central blood pressure and pulse wave velocity	Measured two times with an interval of one week	brachial blood pressure, central blood pressure and pulse wava velocity is measured evrey twenty minutes and averaged for day time and night time. the relative reduction at nioght for the parameters are calculated

Countries

Denmark

Outcome results