Knee Osteoarthritis
Conditions
Brief summary
This is a prospective, observational study, aimed to establish the relationship between an inefficient endogenous pain modulation before surgery (total knee arthroplasty; TKA) and the probability to develop chronic pain after surgery (persistent post surgical pain). Endogenous analgesia efficiency will be measured during the month previous to surgery using quantitative sensory testing (QST). Persistent post surgical pain will be defined as presence of pain in movement greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery.
Interventions
BEHAVIORALQuantitative sensory testing (QST)
Sponsors
Parc de Salut Mar
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Older than 18 patients * Scheduled for primary total knee arthroplasty * Disposition to visits and scheduled tests
Exclusion criteria
* Previous surgery on knee to be operated * Documented peripheral neuropathy * Severe disease or condition that could potentially interfere with interpretation of tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of pain in the operated knee, 6 months after surgery. | Presence of pain greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery. |
Secondary
| Measure | Time frame |
|---|---|
| Endogenous Analgesia efficiency measured with QST (Quantitative sensory testing) techniques. | From start of recruitment untill day 180. |
Countries
Spain
Outcome results
None listed