Erosion; Cornea, Traumatic
Conditions
Keywords
mechanical corneal erosion, bandage contact lens, pressure patching, erosion area, pain scale
Brief summary
This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.
Detailed description
This is a randomized open-label clinical trial in patients with mechanical corneal erosion. Subjects were selected to use bandage contact lens (Senofilcon A) or pressure patching. All subjects received combination of Polymyxin B, Neomycin, and Gramicidin eye drops and 0,5% Tropicamide eye drops. Evaluation was done 24 hours after treatment
Interventions
DEVICEBandage contact lens
Bandage contact lens : contact lenses (material senofilcon A; base curve 8,8 mm; power - 0,50; diameter 14 mm)
DEVICEPressure patching
Pressure patching : using 2 pieces of sterile gauze. The first gauze placed vertically and the second placed horizontally, then fixed with adhesive tape so that eyelid can not move.
Sponsors
Udayana University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
17 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* aged 17-55 years * onset of corneal erosion \< 48 hours * corneal erosion due to mechanical injury * extensive corneal erosion \> 3 mm2
Exclusion criteria
* bilateral corneal erosion * corneal erosion due to chemical or thermal injury * history of systemic analgesic use within 1 week prior to the examination or topical analgesics within 1 hour before the examination * history of systemic or topical antibiotics within 1 week prior to the examination * other abnormalities due to trauma * palpebral or eyelashes position abnormalities * anterior segment infections * tear break-up time \< 7 seconds in the contra lateral eye
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Size of corneal erosion area | 24 hour | Corneal erosion area is the multiplication of the long and short axis of corneal erosion, as measured using a caliper, with the help of fluorescein and cobalt blue slit lamp beam |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain scale | 24 hour | Pain scale assessment conducted using the Visual Analogue Scale (VAS) subjectively |
Other
| Measure | Time frame | Description |
|---|---|---|
| Complication | 24 hour | Complication of corneal erosion (e.g. conjunctivitis, keratitis, corneal ulcer) |
Countries
Indonesia
Outcome results
None listed