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Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Evaluation of the Methods and Management of Acute Coronary Events: 3. Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01808027
Enrollment
5555
Registered
2013-03-08
Start date
2011-02-28
Completion date
2013-02-28
Last updated
2013-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Keywords

quality of life drug adherence drug compliance mortality

Brief summary

To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.

Detailed description

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depends upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation and whether patients take their medication after discharge from hospital. Using powerful statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Interventions

None listed

Sponsors

University of Leeds
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age \> 18 years * Both sexes * Acute admission to the acute Trust with suspected acute coronary syndrome

Exclusion criteria

* Patients at a terminal stage of any illness * Those in whom follow up would be inappropriate or impractical

Design outcomes

Primary

MeasureTime frameDescription
delays to treatment12 monthsQuantification of hospital attributable effects relating to early and late mortality

Secondary

MeasureTime frameDescription
Describing trajectories of quality of life recovery patterns12 monthDescribing trajectories of quality of life recovery patterns

Other

MeasureTime frameDescription
Develop a risk score and a near-point risk Acute Coronary Syndrome modeltwo yearsDevelop a risk score and a near-point risk Acute Coronary Syndrome model

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026