Safety, Immunogenicity And Efficacy Of Vaccination In Military Personnel

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01807780

Enrollment

262

Registered

2013-03-08

Start date

2012-09-30

Completion date

2015-09-30

Last updated

2017-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Specific Antibody Response, Vaccination Adverse Events, Vaccination Failure

Brief summary

The purpose of this study is to determine if multiple vaccination in military personnel may be correlated with the appearance of poorly defined diseases as symptomatic multisyndrome, autoimmune or lymphoproliferative disorders. At the same time, considering possible interference between different vaccines, proteins and polysaccharides, living and inactivated, the study aims to assess the immunogenicity and efficacy also in relation to the specific Human Leucocyte Antigens (HLA) genetic structure.

Interventions

BIOLOGICALbiological monitoring

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* Military volunteers * No recently immunized

Exclusion criteria

* Pregnancy * Documented immunodepression * Documented allergy or hypersensitivity to vaccines

Design outcomes

Primary

Measure	Time frame
immunomediated disorders related to multiple vaccination	three years

Secondary

Measure	Time frame
efficacy of multiple vaccination	Three years
immunogenicity of multiple vaccination	Three years

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026