Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01806948

Enrollment

Registered

2013-03-07

Start date

2013-04-30

Completion date

2014-10-31

Last updated

2016-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Brief summary

We randomized patients who received laparoscopic surgery for benign gynecologic disease into double dose (Experimental Group) or single dose (Control Group) of antiemetics. We compared the degree of postoperative nausea and vomiting in experimental and control groups.

Interventions

DRUGRamosetron

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Laparoscopy for benign gynecologic disease

Exclusion criteria

* Vomiting within 24 hours before surgery * Not using patient controlled analgesics postoperatively

Design outcomes

Primary

Measure	Time frame	Description
Complete Response Rate	Postoperative 24 hours	The percentage of patients who experienced neither nausea nor vomiting within 24 hours after surgery

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026