Allergic Rhinitis, Asthma, Atopic Dermatitis, Healthy, Urticaria
Conditions
Keywords
Children, Asthma, Allergic rhinitis, Atopic dermatitis, Urticaria, Healthy
Brief summary
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide level in children suspected and being diagnosed due to allergic diseases.
Detailed description
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide (FeNO) level in children suspected and being diagnosed due to allergic diseases. Study will be retrospective, conducted in all children diagnosed in the years of 2005-20012 in Laboratory of lung function tests of Department of Pediatrics and Allergy, Medical University of Lodz, N. Copernicus Hospital, Lodz, Poland. The investigators will analyse 5500 male an female children 5-18 year old suspected and being diagnosed due to allergic diseases. In these children nearly 3000 FeNO measurements, 65000 spirometry measurements, 22000 whole-body plethysmography measurements and 48000 occlusion resistance measurements were performed between the years of 2005-2012. The investigators will retrospectively evaluate following data from medical documentation of patients: 1. FeNO levels. 2. Allergic disease diagnosis. 3. Immunoglobulin E (IgE) specific levels. 4. Treatment (drugs and dosages). 5. Lung function parameters (spirometry, whole-body plethysmography, occlusion resistance, bronchial reversibility test).
Interventions
OTHERNo intervention
No intervention
Sponsors
Medical University of Lodz
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
5 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Children with allergic diseases, healthy children.
Exclusion criteria
* Other serious diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Allergic disease diagnosis | 7 years | Allergic disease diagnosis. The diagnosis and the severity of asthma, allergic rhinitis and atopic dermatitis and other allergic diseases universally established by the doctors (allergologists) according to standard definitions of diseases in the latest guidelines |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lung function (LF) | 7 years | spirometry, whole-body pletysmography, occlusion resistance, bronchial reversibility test |
Other
| Measure | Time frame | Description |
|---|---|---|
| Fractional exhaled nitric oxide (FeNO) | 7 years | Fractional exhaled nitric oxide (Sievers equipment) |
| Immunoglobulin E (IgE) allergen specific | 7 years | Immunoglobulin E (IgE) allergen specific (ELISA method) |
| Treatment of asthma (drugs and dosages) | 7 years | Treatment of asthma (drugs and dosages last 3 months before measurement of lung function parameters and FeNO) |
Countries
Poland
Contacts
Primary ContactIwona Stelmach, MDPhDProf
Backup ContactTomasz Grzelewski, MD PhD
Outcome results
None listed