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Cardiac Arrest and Intra Osseous Infusion

Obtaining Vascular Access (Venous or Intraosseous) During Cardiac Arrest in Out-of-hospital Care: Delays and Failure Risk Factors

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01803971
Acronym
ACCIO
Enrollment
200
Registered
2013-03-04
Start date
2012-06-01
Completion date
2013-03-01
Last updated
2026-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

cardiac arrest, peripheral venous access, intraosseous access

Brief summary

the international recommendations don't explain the place of the intraosseous infusion in the reanimation of adult cardiac arrest; the goal of this preliminary study is to inform the delay for obtaining a vascular access by evaluation of a current strategy (using intraosseous infusion after one peripheral venous access failure) and to determine the potential failure risk factors of venous access.

Detailed description

In 2010, the European Resuscitation Council and the International Liaison Commitee on Resuscitation have made new recommendations about management of cardiac arrest. The intraosseous infusion was described as an alternative to the peripheral venous access, before the intra tracheal way for adrenaline administration. But this work doesn't specify the delay and the circumstance for this use: time to obtain a vascular access, number of failure, difficulty to obtain a venous access. Furthermore the recent improvements in intraosseous devices may make it relevant to compare intra osseous infusion and venous access in first intention in adult's cardiac arrest in view of the significant number of venous failures and of the subsequent delay of adrenaline administration. The goal of this preliminary study is to inform the delay to obtain a vascular access by evaluation of a current care (using intravenous infusion after one peripheral venous access failure) and to determine the potential failure's risk factors of venous access. Main objective: estimate the delay to obtain an effective vascular access (peripheral venous access, intra osseous infusion, central venous access) in resuscitation of adult's cardiac arrest by out of hospital care unit according to the international recommendations. Study design: monocentric prospective cohort of consecutive patients presenting with out-of-hospital cardiac arrest.

Interventions

OTHERObtention of vascular access in out-of-hospital cardiac arrest patients according to the current strategy

Current strategy of obtention of a vascular access : first attempt by peripheral venous access and if failure switch to intraosseous route

Sponsors

University Hospital, Bordeaux
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years old or over * patients insured by social security * cardiac arrest (all causes) with mobilisation of a intensive mobile care unit in primary intervention * medical resuscitation indicated

Exclusion criteria

* pregnancy * contraindication osseous infusion

Design outcomes

Primary

MeasureTime frameDescription
functional vascular accessat inclusion (day 0)time for obtaining a functional vascular access from the beginning of out-of-hospital cardiac arrest management

Countries

France

Contacts

STUDY_CHAIRPaul PEREZ, MD, PhD

University Hospital Bordeaux, France

PRINCIPAL_INVESTIGATORBruno SIMONNET, MD

University Hospital Bordeaux, France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 23, 2026