Healthy
Conditions
Keywords
children
Brief summary
Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.
Interventions
DIETARY_SUPPLEMENTcreatine supplementation
creatine supplementation
DIETARY_SUPPLEMENTPlacebo
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
10 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy children * age between 10 to 12 years of age
Exclusion criteria
* cognitive impairment * vegetarian diet * use of creatine in the past 6 months * chronic kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cognitive function | 7 days | assessed by a battery of cognitive tests as follows: colors and words attention test, controlled words association test, memory and figures learning, mental flexibility test and inhibitory control, digit span test, and intelligence quotient. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| tissue creatine content | 7 days | as assessed by 1H-MRS. |
Countries
Brazil
Contacts
Primary ContactCarlos Merege
Outcome results
None listed