The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome

Key Technology Research of the Comprehensive Treatment of Multiple Organ Dysfunction Syndrome

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01802983

Enrollment

Registered

2013-03-04

Start date

2009-01-31

Completion date

2013-12-31

Last updated

2013-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Organ Dysfunction Syndrome

Keywords

Aged, Multiple organ failure, Extubation, Prognosis, MODS, invasive mechanical ventilation

Brief summary

The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 60 years old; * presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention; * have trachea intubation after admitting to intensive care unit within 24 hours.

Exclusion criteria

* end stage multiple organ failure.

Design outcomes

Primary

Measure	Time frame	Description
the prognostic assessment of aged patients with MODS	28 days	According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems \[(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)\], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.

Countries

China

Contacts

Primary ContactXiao Kun, doctor

xiaok301@163.com+8613716608331

Outcome results