Symptomatic Aortic Valve Stenosis
Conditions
Keywords
TAVI, complete AV-block, HV-interval, permanent pacemaker
Brief summary
The development of a high grade AV-block is a frequent complication associated with transcatheter aortic valve implantation (TAVI). Patients who were suitable for TAVI will be enrolled in this study. The HV-interval will be determined before and immediately after implantation. The hypothesis is that a prolonged HV-interval is associated with a high rate of complete AV-block following TAVI.
Interventions
None listed
Sponsors
Klinik für Kardiologie, Pneumologie und Angiologie
Study design
Observational model
COHORT
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* symptomatic aortic valve stenosis * patients screened for TAVI * written informed consent
Exclusion criteria
* unconsciousness, not able to consent * \< 18 years * permanent pacemaker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Determination of HV interval | Changes in Baseline to 24 hours | HV-interval will be determined by a 5F quadripolar electrode catheter with a CRD-2 curve configuration. Intracardiac signals will be assessed and determined before and after implantation. |
Secondary
| Measure | Time frame |
|---|---|
| AV-block development after 1 month, 6 months and 12 months | 1 month, 6 months and 12 months |
Other
| Measure | Time frame |
|---|---|
| cardiovascular mortality | 1 month, 6 months and 12 months |
Countries
Germany
Outcome results
None listed