EtCO2 Monitoring in Acute Self-poisoning

Continuous EtCO2 Monitoring in Acute Self Poisoned Patients Admitted in an Emergency Department

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01800123

Acronym

CAPNOTOX

Enrollment

200

Registered

2013-02-27

Start date

2012-03-31

Completion date

Unknown

Last updated

2013-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Intentional Overdose

Keywords

Intoxication, overdose, poisoning, EtCO2, emergency medicine

Brief summary

There is no consensus on monitoring criteria in acute self poisoning. Clinical scores, vital signs or lactatemia have failed to prove good predictive value. The main acute self poisoning complication is decreased consciousness level with consequent increased risk of hypoxemia and aspiration pneumonitis. Several clinical studies have recently shown that EtCO2 monitoring can be valuable in procedural sedation in the emergency department. It is able to predict hypoxemia before any SaO2 decrease and any complications related to these procedures. We therefore hypothesized that EtCO2 could help in acute self poisoning patients' monitoring in the ED.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* \>18y/o * acute self poisoning patients * patients requiring monitoring according to physician's opinion * patients not requiring invasive ventilation at ED admission

Exclusion criteria

* Pregnant woman * patients deprived of liberty

Design outcomes

Primary

Measure	Time frame	Description
ROC curve of maximal EtCO2 to predict poisoning complication	During the first 2 hours of ED admission	Poisoning complications are defined as: Hypoxia (Spo2\<93%) and/or Respiratory rate \<10/min or \>25/min and/or ICU admission and/or Oro tracheal intubation

Countries

France

Outcome results