Research of Revascularization in Immature Teeth With Periapical Periodontitis

Randomized Controlled Research of Revascularization in Immature Permanent Teeth With Periapical Periodontitis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01799187

Enrollment

190

Registered

2013-02-26

Start date

2012-07-31

Completion date

2021-07-31

Last updated

2014-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periapical Periodontitis

Keywords

Immature Permanent Teeth

Brief summary

Revascularization is an alternative new treatment of immature permanent teeth with necrotic pulp nowadays while apexification is the traditional therapy. The investigators suppose that revascularization is superior to apexification at developing the root of immature permanent teeth and reducing the risk of root fracture,and the research is designed.

Detailed description

The investigators design to collect a group of patients presenting immature permanent teeth with periapical periodontitis in certain criterion. The investigators will divide the patients into two groups randomly. One group will get treated with revascularization while the other with apexification. The investigators want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of revascularization.

Interventions

PROCEDURErevascularization

revascularization include 3 steps: root disinfected,induction of bleeding and revascularization include 3 steps: root disinfected,induction of bleeding and sealing

PROCEDUREapexification

apexification uses calcium hydroxide as root medication

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

6 Years to 18 Years

Healthy volunteers

Yes

Inclusion criteria

* clinical diagnosis of periapical periodontitis * must be immature permanent teeth * must be local Guangzhou

Exclusion criteria

* blood disease * residual root that is advised to extract * serious periodontitis * women in pregnancy

Design outcomes

Primary

Measure	Time frame
Evidence of lesion healing confirmed by cone beam computed tomography	one year

Countries

China

Contacts

Primary ContactLing J Qi, PhD

lingjq@mail.sysu.edu.cn020-83863002

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026