Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01799018

Enrollment

Registered

2013-02-26

Start date

2011-04-30

Completion date

2013-06-30

Last updated

2014-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Vasospasm, Hydrocephalus, Subarachnoid Hemorrhage

Keywords

Xanthine Oxidase, Cerebrospinal fluid

Brief summary

The purpose of this study is to determine the role of Proteomics and Metallomics in Cerebral Vasospasm following Subarachnoid Hemorrhage

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 89 Years

Healthy volunteers

Inclusion criteria

* Non traumatic SAH documented by CT scan * Patient with SAH who would need external ventricular drain (EVD) for the management of hydrocephalus * Patients with normal pressure Hydrocephalus that require an external drain * Control (non - hemorrhagic) group - CSF collected from patients with posterior fossa tumor or stroke with EVD in place for the management of hydrocephalus.

Exclusion criteria

* Recent infection within last 1 month of presentation- can increase inflammatory markers * Recent surgery or acute myocardial infarction within last 1 month of presentation * Age \> 89 years or \< 18 years

Design outcomes

Primary

Measure	Time frame
Protein identification and concentration	For the duration of CSF drainage, or until the 21st day after admission.
Metal ion identification and concentration	For the duration of CSF drainage, or until the 21st day after admission.

Countries

United States

Outcome results