Chronic Obstructive Pulmonary Disease, Diabetes
Conditions
Keywords
COPD, Diabetes, steroids, Hemoglobin A1C DIFFERENCE
Brief summary
Corticosteroid treatment in diabetic patients admitted for COPD exacerbation are expected to significantly increase hemoglobin A1C levels
Detailed description
HbA1C levels were evaluated in diabetic patients with COPD exacerbation on admission to the hospital and 3-months later. Demographic, clinical, laboratory variables and total steroid dose were documented. Age- and sex-matched group of diabetic patients with COPD who were admitted for other reasons, were asked to participate as a control group. Mann-Whitney and Chi square/Fischer's exact tests were used to compare between the parameters of the two groups. Wilcoxon signed rank test was used to compare between HbA1C levels at baseline and 3 months later. Multi-variate linear regression analysis was used to find predictors for increase in HbA1C levels in the patients' group.
Interventions
None listed
Sponsors
The Nazareth Hospital, Israel
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diabetic patients with COPD exacerbation
Exclusion criteria
* Patients treated with steroids during the previous 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin A1C LEVEL | 3 MONTHS |
Secondary
| Measure | Time frame |
|---|---|
| Glucose levels | 3 months |
Other
| Measure | Time frame |
|---|---|
| Weight | 3 months |
Countries
Israel
Outcome results
None listed