Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)

Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI): an Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01796210

Enrollment

Registered

2013-02-21

Start date

2012-10-31

Completion date

2013-05-31

Last updated

2013-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

Analgesia/nociception index, Bispectral index, Propofol, Remifentanil, Suspension laryngoscopy, Endoscopy, Ear-nose-throat

Brief summary

The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.

Detailed description

Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age 18-75 years * Suspension laryngoscopy for diagnostic or therapeutic purposes * Total intravenous anesthesia using propofol and remifentanil

Exclusion criteria

* age \<18 yrs or \>75 yrs * arrythmia * administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes * psychiatric diseases * autonomic nervous system disorders (epilepsy)

Design outcomes

Primary

Measure	Time frame
Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes	Before induction of anesthesia, 1 min after beginning of procedure, at steady-state anesthesia during procedure (an expected average of 10 min) and at arousal from general anesthesia in the end of procedure (an expected average of 20 min)

Countries

France

Outcome results