Asthma
Conditions
Keywords
Asthma, Nebulizers, Salbutamol, Developing Countries
Brief summary
This is an equivalence study comparing an electric nebulizer with a human-powered nebulizer--one that does not need electricity--in the treatment of mild to moderate asthma exacerbations in a regional clinic in San Salvador, El Salvador.
Detailed description
The study design is to treat individuals suffering from mild to moderate exacerbations of asthma with nebulized salbutamol (2.5mg). Subjects will receive nebulization using either an electric nebulizer compressor or a human-powered nebulizer compressor. Improvement in peak expiratory flow will be the primary endpoint. Blood oxygenation levels as measured by pulse oximetry will be a secondary endpoint of the trial.
Interventions
DEVICEHuman-Powered Nebulizer
Sponsors
Marquette University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Suffering from Mild or Moderate Asthma symptoms * Increased respiratory rate, but not over 30 breaths per minute * Reduced peak expiratory flow rate, but not less than 60% of normal * Oxygen saturation levels reduced but greater than 90%
Exclusion criteria
* Any other respiratory condition that would interfere with nebulizer treatment * If any other medication is being taken at the time * Pregnant women or women who may think they might be pregnant * Never taken salbutamol before
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in Peak Expiratory Flow | From before to after nebulizer treatment lasting approximately 30 minutes |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in blood oxygenation as measured by pulse oximetry | From before to after nebulizer treatment lasting about 30 minutes |
Countries
El Salvador
Outcome results
None listed