Aortic Stenosis, Symptomatic Aortic Stenosis, Valvular Heart Disease
Conditions
Keywords
HRQoL, Aortic stenosis, Aortic valve surgery
Brief summary
Our main hypothesis on the present study is that new parameters such as risk-taking behavior, patients motivation, health related quality of life, new biomarkers and more precise echocardiography measures in addition to traditional parameters will improve pre-operative risk assessment in patients with AS and better guide patients and doctors in decision whether to operate or not.
Detailed description
Patients referred for surgery are included thorough reading referral letter. Data collected in the study wil be compared with data from Medical records and clinical examination. Data entered will be controlled by two investigators. Data wil be compared to national norms and from result of other studies.
Interventions
None listed
Sponsors
Oslo University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients above 18 years with symptomatic AS referred to preoperative examination.
Exclusion criteria
* Exclusion: Patients who do not want to participate. Patients not able to speak and read Norwegian.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death due cardiovascular events | one year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| MACE ( Major cardiovascular events ) | 30 days | Cerebral complications (stroke/bleeding), bleeding, renal failure, arrythmias, needs for pacemaker, prolong ICU stay, wound infections |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in Health related Quality and function one year after inclusion | one year | Patients in the study perform Short Form-36, EuroQual-5D at inclusion and one year after. We want to compare the result of their scoring to obtain the gain in HRQoL of the intervention |
| Hospital visit and use of Health services last years | 30 days | — |
Countries
Norway
Contacts
Primary ContactAmjad I Hussain, Md
Outcome results
None listed