Extravasation of Diagnostic and Therapeutic Materials, Infection of Intravenous Catheter, Phlebitis
Conditions
Keywords
peripheral venous catheter, children.
Brief summary
The aim of the study is to verify if the periodic flush with normal saline 0.9% NaCl causes a longer or equal duration of patency of peripheral venous catheters, compared with heparin solution 50 U / ml flush, in children from 2 years to 14 years. Only 22 and 24 gauge catheters Will be included in the study.The study will assess in particular: * the difference of permanence in situ of the device * the difference in incidence of complications (in detail: obstruction, phlebitis, thrombocytopenia, systemic anticoagulation) * the difference in costs between use of saline normal saline 0.9% NaCl solution and heparinized 50 U / ml.
Interventions
DRUG0,9% NaCl flush
Normal Saline solution
DRUGHeparin 50U/ml
Heparin solution
Sponsors
University of Florence
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
2 Years to 14 Years
Healthy volunteers
No
Inclusion criteria
* Age between 2 years and 14 years old * Medical prescription of intravenous antibiotic therapy for at least 2 doses on the day * Presence of informed consent to participate to the study provided by the parents * No known hypersensitivity to heparin * No known hypersensitivity to the patch fixing materials (polyurethane and / or glue) * Absence of diseases buoyancy coagulation (haemophilias and / or thrombophilias) * No antecedents trombopenie dued to the use of any type of heparin or a pentosan polysulfate * No existing treatment based on corticosteroids and / or anti-inflammatory
Exclusion criteria
* age outside the range 2 - 14 years * children for which there is no prescription of intravenous antibiotic therapy for at least 2 times a day * children for which the parents have not consented to the study * children with known hypersensitivity to heparin * children with known hypersensitivity to the patch fixing materials (polyurethane and / or adhesive) * children with disease-causing buoyancy coagulation (Hemophilia and / or thrombophilia) * children with antecedents of trombopenie occurring by the use of any type of heparin or of a pentosan polyphosphate * children in treatment with corticosteroids and / or anti-inflammatory
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average length of stay on site of the catheter measured in hours | participants will be followed for the duration on site of the first peripheral venous catheter inserted to each recruited subject, i.e. for an expected average of 10 dayse |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of complications extimated overall and by type of complication | participants will be followed for the duration on site of the first peripheral venous catheter inserted to each recruited subject, i.e. for an expected average of 10 days |
| Average cost for the maintenance of the catheter of each subject (pro day and in total) | participants will be followed for the duration on site of the first peripheral venous catheter inserted to each recruited subject, i.e. for an expected average of 10 days |
Countries
Italy
Outcome results
None listed