Transradial and Transfemoral Coronary Angiography by EXPERienced operaTors

Transradial and Transfemoral Approach by EXPERienced Operators in Daily rouTine (EXPERT): a Randomized, Non-inferiority Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01794325

Acronym

EXPERT

Enrollment

300

Registered

2013-02-18

Start date

2013-02-28

Completion date

2014-03-31

Last updated

2014-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease, Exposure to Ionizing Radiation, Vascular Access Complication

Keywords

Occupational radiation exposure, Transradial approach, Transfemoral approach

Brief summary

Transradial approach (TRA) reduces vascular complications and access related-bleeding compared to transfemoral approach (TFA). However, this technique has been related to higher radiation exposure during coronary angiography and percutaneous coronary intervention. Previous studies have shown that TRA demands a long learning curve, and procedure success rate increases with operator's experience. Our hypothesis is that the higher radiation exposure during TRA is not a technique issue, but due to operator's expertise. The aim of this study is to evaluate whether experienced operators with either TRA or TFA can perform diagnostic coronary angiography with similar radiation exposure.

Interventions

OTHERTrans-radial

Coronary angiography performed through trans-radial access

OTHERTrans-femoral

Coronary angiography performed through trans-femoral access

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Indication for a elective coronary angiography * Eligible for either transfemoral or transradial approach * Accept to sign the written consent form (WCF)

Exclusion criteria

* Refusal to sign the WCF * End stage renal failure * Urgency/Emergency procedure * Contraindication to perform both coronary and left ventricle angiogram * Necessity of another vascular angiogram during coronary angiography

Design outcomes

Primary

Measure	Time frame	Description
Patient radiation exposure (mGy)	during coronary angiography	Patient radiation exposure (mGy)

Secondary

Measure	Time frame	Description
Physician radiation exposure (in uSv)	during coronary angiography	Physician radiation exposure (in uSv)

Other

Measure	Time frame	Description
Major adverse cardiac events	30 days	Major adverse cardiac events (death, stroke and vascular complications)

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026